Insufficient and excessive sleep associated with accelerated aging
An analysis of biological clocks across the human body suggests that both insufficient and excessive sleep may accelerate aging in the brain, heart, lungs, and immune system. …
How eating primes immune cells for future responses
Eating induces a temporary metabolic state that enhances the function and metabolic activity of T cells, potentially improving immune responses and the effectiveness of T cell–based therapies. …
mRNA vaccines follow unconventional immune path to destroy tumors
mRNA vaccines can trigger strong anti-tumor immune responses through an unexpected immune cell mechanism. …
A new view of aging: How the immune system rewrites rapid aging
New research shows that dialing down an overactive immune sensor can restore tissue health in severe genetic disorders, reshaping how scientists think about aging and DNA damage. …
How pancreatic cancer blocks immunotherapy
Researchers have uncovered a key reason why immunotherapy has largely failed in pancreatic cancer and have identified a promising strategy to overcome this resistance. …
Amino acid cysteine fuels cancer-fighting T cells
Research shows that the amino acid cysteine promotes the production of the antioxidant glutathione, which regulates T-cell activity, and also supports T-cell proliferation and maintenance of their cancer-fighting function. …
Gut primes pathogenic T cells responsible for neuroinflammation in multiple sclerosis
Researchers identify the role of gut-derived cells in antigen presentation as a key initiator of autoimmune neuroinflammation. …
Vitamin D regulates immune response to gut microbiome in inflammatory bowel disease
Vitamin D supplementation may help shape how the immune system responds to gut bacteria in people with inflammatory bowel disease. …
How the immune system triggers a loss of appetite
Scientists have traced the molecular pathway connecting the gut immune system to the brain during a parasitic infection, explaining how the immune response triggers loss of appetite. …
Enhanced brain cells clear dementia-related amyloid beta peptides
A single injection of a new cellular immunotherapy prevents and reduces amyloid plaques in mice. …
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