Engineered immune cells may be able to tame inflammation
Immune cells that are designed to soothe inflammation could improve treatment for organ transplants, type 1 diabetes and other autoimmune conditions. …
Study reveals how aging impairs antitumor immunity
Aging specifically impairs the generation of CD8+ tissue-resident memory T cells and thus compromises antitumor immunity. …
Study reveals how cancer immunotherapy may cause heart inflammation in some patients
Cancer immunotherapy-associated heart inflammation is driven by an immune response distinct from the anti-tumor response, indicating that this serious complication might be managed without stopping cancer therapy. …
Novel combination immunotherapy shows promise in treating melanoma
A phase 2 clinical trial found that pre-surgery treatment with the novel drug vidutolimod and the PD-1 checkpoint inhibitor nivolumab led to tumor control in 55 percent of patients with stage 3 cutaneous melanoma. …
Healthy brains suppress inappropriate immune responses
A study in mice found that immune-stimulating protein fragments, called guardian peptides, are produced by the brain and spinal cord to maintain the brain’s immune balance, allowing for healthy communication with the immune system. …
Discovery reveals how ovarian tumors disable immune cells
Researchers have discovered a mechanism that ovarian tumors use to weaken immune cells and hinder their attack by blocking the energy supply that T cells rely on. …
Scientists discover that special immune cells stop cancer metastasis
New research has identified a natural immune mechanism in mice that prevents cancer metastasis. …
Researchers discover new role of immune cells in eye health
Study reveals new understanding of the eye’s natural defense against uveitis and inflammation. …
New combination treatment brings hope to patients with advanced bladder cancer
Findings from the international FORT-2 clinical trial indicate that a promising combination treatment that includes immunotherapy is safe and well-tolerated in patients with locally advanced or metastatic bladder cancer. …
Novel immunotherapy improves recovery from spinal cord injury
Scientists have developed an immunotherapy that protects neurons from immune cell attack at the site of traumatic spinal cord injury. …
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