A phase 2 clinical trial found that an investigational anti-IL-6 antibody sustainably reduced inflammation biomarkers for six months in patients with chronic kidney disease and elevated cardiovascular risk. …
New research shows that the specialized immune cell dendritic cell type 1 is crucial for forming and sustaining tertiary lymphoid structures, which act as local immune hubs coordinating antitumor immunity. …
Two companion studies show that mezigdomide can reverse T cell exhaustion and improve the effectiveness of CAR T-cell therapy and bispecific antibody treatments, which are already transforming the standard of care for multiple myeloma. …
Researchers discovered that certain immune cells in early-life skin are more reactive than in adults, which may explain why eczema often begins in childhood. …
New study reveals why timing of identical mutations in childhood leukemia can produce very different outcomes, opening the door to more precise therapies. …
Researchers have reported early success with a novel mRNA-based therapy that slowed bacterial growth, boosted immune response and reduced lung tissue damage in preclinical models of multidrug-resistant pneumonia. …
Researchers analyzed over a thousand 3D structures of antibodies bound to the SARS-CoV-2 spike protein, creating a structural atlas that reveals how the immune system targets the virus and how SARS-CoV-2 evolves to evade it. …
New research shows lung cancer weakens the immune system by reprogramming bone marrow immune cells before they reach tumors, suggesting a potential target to improve immunotherapy. …
Even the most advanced artificial intelligence models can make surprisingly simple mistakes when faced with complex medical ethics scenarios. …
A new lipid nanoparticle system enables intravenous delivery of mRNA to the brain, overcoming the blood-brain barrier and potentially expanding treatment options for neurological and psychiatric diseases. …
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