Posts by Johns Hopkins Medicine
Multimodal genomic analyses predict response to immunotherapy in lung cancer patients
Researchers have developed an integrated genomic approach that potentially could predict which patients with non-small-cell lung cancer will respond to immune checkpoint inhibitors. …
Read Full Article‘Swiss cheese’ bones could be cause of unexplained low back pain
The vast majority of low back pain may be rooted in an overgrowth of pain-sensing nerves into spinal cartilaginous tissue. …
Read Full ArticleSome learning is a whole-brain affair
Researchers used a laser-assisted imaging tool in mice to show that motor-based learning can occur in multiple areas of the brain, even ones not typically associated with motor control. …
Read Full ArticleIntermittent fasting: live ‘fast,’ live longer?
New review article examines the scientific evidence behind intermittent fasting. …
Read Full ArticleGenetic brain disorder fixed in mice using precision epigenome editing
Using a targeted gene epigenome editing approach in the developing mouse brain, researchers reversed one gene mutation that leads to the genetic disorder WAGR syndrome, …
Read Full ArticleNanocontainer ships titan-size gene therapies and drugs into cells
Scientists have created a tiny, nanosize container that can slip inside cells and deliver protein-based medicines and gene therapies of any size …
Read Full ArticleHelper protein worsens diabetic eye disease
In a recent study using mice, lab-grown human retinal cells and patient samples, scientists found evidence of a new pathway that may contribute to degeneration of the light-sensitive tissue at the back of the eye. …
Read Full ArticleGlutamine-blocking drug slows tumor growth and strengthens anti-tumor response
A compound that blocks glutamine metabolism can slow tumor growth, alter the tumor microenvironment and promote the production of durable and highly active anti-tumor T cells. …
Read Full ArticleOxygen-starved tumor cells have survival advantage that promotes cancer spread
Researchers say they have significant new evidence that tumor cells exposed to low-oxygen conditions have an advantage when it comes to invading and surviving in the bloodstream. …
Read Full ArticleDrug treats inflammation associated with genetic heart disease
When young athletes experience sudden cardiac death as they run down the playing field, it’s usually due to arrhythmogenic cardiomyopathy (ACM), an inherited heart disease. …
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