Posts by Johns Hopkins Medicine
Glutamine-blocking drug slows tumor growth and strengthens anti-tumor response
A compound that blocks glutamine metabolism can slow tumor growth, alter the tumor microenvironment and promote the production of durable and highly active anti-tumor T cells. …
Read Full ArticleOxygen-starved tumor cells have survival advantage that promotes cancer spread
Researchers say they have significant new evidence that tumor cells exposed to low-oxygen conditions have an advantage when it comes to invading and surviving in the bloodstream. …
Read Full ArticleDrug treats inflammation associated with genetic heart disease
When young athletes experience sudden cardiac death as they run down the playing field, it’s usually due to arrhythmogenic cardiomyopathy (ACM), an inherited heart disease. …
Read Full ArticleMetabolic inhibitor extends survival in mice with certain pediatric brain tumors
Versions of an antibiotic drug called DON first isolated from soil bacteria more than 60 years ago have shown promising signs of extending survival in mice models of especially lethal pediatric brain tumors …
Read Full ArticleStem cells with ‘dual identity’ linked to loss of smell from sinus inflammation
Researchers report evidence that neuronal stem cells in the part of the nose responsible for the sense of smell transform themselves to promote long-term inflammation in chronic sinusitis. …
Read Full ArticleTransplanted mouse brain stem cells survive without anti-rejection drugs
In experiments in mice, researchers have developed a way to successfully transplant certain protective brain cells without the need for lifelong anti-rejection drugs. …
Read Full ArticleBreast cancer cells ‘stick together’ to spread through the body during metastasis
Researchers discovered that a cell adhesion protein, E-cadherin, allows breast cancer cells to survive as they travel through the body and form new tumors, …
Read Full ArticleHigh-fat diet during pregnancy slows learning in offspring, rat study suggests
Researchers have found that pregnant and nursing rats fed high-fat diets have offspring that grow up to be slower than expected learners …
Read Full ArticleAntibiotics exposure linked to increased colon cancer risk
Extensive “data mining” analysis of British medical records suggests that taking even a single course of antibiotics might boost – albeit slightly – the risk of developing colon cancer …
Read Full ArticleAbnormal blood pressure in middle and late life influences dementia risk
New findings suggest that abnormal blood pressure in midlife persisting into late life increases the likelihood of developing dementia. …
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