Classifying childhood brain cancers by immune response may improve diagnostics and treatments
A new way to profile brain cancers in children paves the way for improved diagnostics and treatments. …
Breakthrough in next-generation polio vaccines
Researchers are advancing a safer and more affordable polio vaccine by utilizing virus-like particles that mimic the poliovirus’s outer protein shell without containing any infectious material. …
Alzheimer’s treatment may lie in the brain’s own immune cells
A study on Alzheimer’s patients who received amyloid-beta-targeted immunotherapy may change future treatments by shifting the focus from removing amyloid plaques to using the brain’s natural immune defenses. …
Breakthrough study reveals genetic mutation that could serve as basis for new rheumatoid arthritis treatment
New findings reveal that a specific mutation in a protein called TRAF1 can shut down an overactive immune response, dramatically reducing inflammation in mice and potentially paving the way for a new class of drugs to treat rheumatoid arthritis. …
Designing self-destructing bacteria to make effective tuberculosis vaccines
Working toward more effective tuberculosis vaccines, researchers have developed two strains of mycobacteria with “kill switches” that can be triggered to stop the bacteria after they activate an immune response. …
Autoimmune response may lead to more Parkinson’s cases in men
Researchers have identified an autoimmune response and a specific autoantigen in brain cells that could explain the higher prevalence of Parkinson’s disease in men and provide a new therapeutic target. …
SSRI antidepressants can protect against infections and sepsis by regulating immune response
Scientists have discovered how SSRI antidepressants regulate the immune response and prevent sepsis in mice, demonstrating a potential new use for these popular drugs. …
Mitochondrial transfer in the tumor microenvironment enables immune evasion
New findings reveal a previously unknown mechanism of cancer immune evasion through mitochondrial transfer, potentially contributing to the development of future cancer immunotherapies. …
Researchers discover how cigarette smoke impairs critical lung immune cells
Researchers reveal how multiple chemicals found in cigarette smoke and e-cigarettes alter the function of a key type of immune cell found in the lungs. …
Engineered immune cells may be able to tame inflammation
Immune cells that are designed to soothe inflammation could improve treatment for organ transplants, type 1 diabetes and other autoimmune conditions. …
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