Engineered immune cells may be able to tame inflammation
Immune cells that are designed to soothe inflammation could improve treatment for organ transplants, type 1 diabetes and other autoimmune conditions. …
Enzyme identified as new therapeutic target for cold tumors
Drugs that suppress the UBA1 enzyme could make immune checkpoint blocking immunotherapy effective for patients with prostate cancer and other cold tumors. …
Fine particulate air pollution may play a role in adverse birth outcomes
A new study finds that exposure to fine particulate matter (PM2.5) air pollution during pregnancy is associated with altered immune responses that can lead to adverse birth outcomes. …
Study reveals how aging impairs antitumor immunity
Aging specifically impairs the generation of CD8+ tissue-resident memory T cells and thus compromises antitumor immunity. …
How vagus nerve stimulation could ease inflammatory bowel disease
A new study reveals how electrical stimulation of the vagus nerve—a major nerve connecting the brain and gut—may help reduce the stress-related inflammation that worsens inflammatory bowel disease symptoms. …
New insights reveal how house dust mites trigger allergic asthma by activating the immune system
New research in mice uncovers how inhaled house dust mites, a common trigger of allergic asthma, activate the immune system and drive this disease. …
Drug combination prompts immune response in some resistant pancreatic cancers
A new drug strategy that regulates the tumor immune microenvironment may make resistant pancreatic cancer tumors responsive to immunotherapy. …
Epigenetic therapy makes glioblastoma cells visible to attacking immune cells
Scientists employed epigenetic therapy to induce glioblastoma cells to express immune system targets, thereby potentially rendering them visible to immune cells and increasing their susceptibility to immunotherapies. …
Study reveals how cancer immunotherapy may cause heart inflammation in some patients
Cancer immunotherapy-associated heart inflammation is driven by an immune response distinct from the anti-tumor response, indicating that this serious complication might be managed without stopping cancer therapy. …
Healthy brains suppress inappropriate immune responses
A study in mice found that immune-stimulating protein fragments, called guardian peptides, are produced by the brain and spinal cord to maintain the brain’s immune balance, allowing for healthy communication with the immune system. …
End of content
End of content
