Classifying childhood brain cancers by immune response may improve diagnostics and treatments
A new way to profile brain cancers in children paves the way for improved diagnostics and treatments. …
Autoimmune response may lead to more Parkinson’s cases in men
Researchers have identified an autoimmune response and a specific autoantigen in brain cells that could explain the higher prevalence of Parkinson’s disease in men and provide a new therapeutic target. …
Rare side effect of cancer immunotherapy
A clinical case report provides important genetic insights into the development of T cell lymphoma following immunotherapy for multiple myeloma. …
Mitochondrial transfer in the tumor microenvironment enables immune evasion
New findings reveal a previously unknown mechanism of cancer immune evasion through mitochondrial transfer, potentially contributing to the development of future cancer immunotherapies. …
New cellular immunotherapy approach shows promise for B-cell lymphoma
Stem-cell-derived chimeric antigen receptor (CAR) natural killer cells show potential for treating B-cell lymphomas and could make future cellular immunotherapies less expensive and more accessible to patients. …
High blood glucose weakens immunity against viral infections in type 2 diabetes patients
New research has identified a mechanistic link between high blood glucose levels and weakened immunity against viral infections in patients with type 2 diabetes. …
Engineered immune cells may be able to tame inflammation
Immune cells that are designed to soothe inflammation could improve treatment for organ transplants, type 1 diabetes and other autoimmune conditions. …
Enzyme identified as new therapeutic target for cold tumors
Drugs that suppress the UBA1 enzyme could make immune checkpoint blocking immunotherapy effective for patients with prostate cancer and other cold tumors. …
Study reveals how aging impairs antitumor immunity
Aging specifically impairs the generation of CD8+ tissue-resident memory T cells and thus compromises antitumor immunity. …
Drug combination prompts immune response in some resistant pancreatic cancers
A new drug strategy that regulates the tumor immune microenvironment may make resistant pancreatic cancer tumors responsive to immunotherapy. …
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