Engineered natural killer cells can eliminate glioblastoma stem cells
Deleting the TGF-beta receptor in natural killer cells overcame immune suppression and enabled anti-tumor activity against glioblastoma stem cells in preclinical models. …
Deleting the TGF-beta receptor in natural killer cells overcame immune suppression and enabled anti-tumor activity against glioblastoma stem cells in preclinical models. …
Preclinical study suggests optic nerve activity promotes the formation of vision-harming tumors in young children with neurofibromatosis type 1 (NF1) cancer predisposition syndrome. …
Two experimental drug approaches that target vulnerabilities in cancer cell metabolism may extend survival and enhance the effectiveness of standard chemotherapies for pediatric brain cancer. …
Regulatory T cells in the brain can be reprogrammed from guarding glioblastoma tumors to attacking them from within. …
The POT1 gene associated with glioma risk, the most common type of malignant brain tumor, mediates its effects in a sex-specific manner. …
Scientists have discovered a potential new target for immunotherapy of malignant brain tumors. …
Study identifies a drug combination that in animal studies and 3D tumor models is spectacularly effective in eradicating diffuse intrinsic pontine glioma (DIPG) tumors. …
Genetic analysis of glioblastoma brain tumors treated with poliovirus therapy suggests a predictive biomarker for survival. …
Up to 20% of glioblastomas–an aggressive brain cancer–are fueled by overactive mitochondria and may be treatable with drugs currently in clinical trials. …
A new study suggests a link between toxoplasma gondii (T. gondii) infection and the risk of glioma, a type of brain cancer, in adults. …
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