Posts by Baylor College of Medicine
Premature epigenomic aging acts like a ‘sleeper cell’ that is awaken by Western-style diet
A new study found that even brief exposure to endocrine-disrupting chemicals while the liver is developing, prematurely aged the liver epigenome and caused metabolic dysfunction in adulthood. …
Read Full ArticleA promising new treatment for recurrent pediatric brain cancer
A novel approach in the treatment of pediatric brain cancer delivers appropriately-targeted chimeric antigen receptor (CAR) T cell therapy directly into the cerebrospinal fluid that surrounds the tumor. …
Read Full ArticleForm of severe childhood malnutrition linked to DNA modification
Researchers have identified significant differences at the epigenetic level between two clinically distinct forms of acute childhood malnutrition. …
Read Full ArticleScientists create ‘epigenetic couch potato’ mouse
Researchers found that changes in DNA methylation in neurons within a part of the brain called the hypothalamus have a major impact on levels of voluntary exercise behavior. …
Read Full ArticleMeningioma molecular profile reliably predicts tumor recurrence
Although typically benign, about one-fifth of meningiomas, the most common primary brain tumors, recur despite complete surgical removal. …
Read Full ArticleGut-brain connection helps explain how overeating leads to obesity
A new study by a multi-institutional team reveals a previously unknown gut-brain connection that helps explain how those extra servings lead to weight gain. …
Read Full Articlep53 mutations in 10,000 cancer patients shed new light on gene’s function
Researchers have conducted the most comprehensive study of TP53 mutations to better understand the processes leading to the inactivation of this important gene in cancer. …
Read Full ArticleDe-escalating breast cancer therapy; can some patients be spared chemotherapy?
About one of every five breast cancers presents with high levels of HER2 proteins. Known as HER2-positive breast cancer, these tumors typically show aggressive behavior …
Read Full ArticleAnalyzing colon cancer proteins and genes uncovers new potential treatments
Analyzing both the entire set of genes and all the proteins produced by colon cancer tissues from patient samples has revealed a more comprehensive view of the tumor …
Read Full ArticleSteroid receptor coactivator-1 variants linked to human obesity
A team led by researchers at Baylor College of Medicine and the University of Cambridge reports that the gene SRC-1 affects body weight control by regulating the function of neurons in the hypothalamus …
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