The experimental drug NU-9 significantly reduced toxic amyloid beta oligomers and related neuronal damage in a mouse model of Alzheimer’s disease, demonstrating potential as an early therapeutic intervention. …
Individual genetic differences can cause antibody-based therapies to be ineffective in some people. …
Study identifies a species of gut bacteria that improves metabolic health and reduces weight gain in mice, suggesting the potential for weight control by modifying gut bacteria. …
A blood test may help doctors determine which colon cancer patients should receive anti-inflammatory medication alongside chemotherapy after surgery, potentially improving personalized treatment and outcomes. …
Biologists have developed a new method using CAR T-cell therapy to stimulate growth and repair of the intestinal epithelium, potentially advancing treatments for age-related gut disorders.
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Researchers have shown that the mitochondrial protein COX7RP increases healthy longevity in mice by improving mitochondrial energy efficiency. …
New research in mice reveals how immune tolerance prevents attacks on healthy tissue and suggests ways to treat cancer, autoimmune disorders, and transplant rejection. …
An off-the-shelf dual-antibody therapy can produce deep and durable responses in extramedullary multiple myeloma, one of the most aggressive and treatment-resistant forms of the disease. …
In a major step toward precision therapy for C. difficile infection, researchers have uncovered how the body’s bile acids bind to and block the bacterium’s most dangerous toxin. …
New study reveals why timing of identical mutations in childhood leukemia can produce very different outcomes, opening the door to more precise therapies. …
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