Posts by Brigham and Women's Hospital
Nanoparticle drug-delivery system developed to treat brain disorders
Use of a nanoparticle drug-delivery system in mouse models results in unprecedented siRNA penetration across the blood-brain barrier. …
Read Full ArticleModerna COVID-19 vaccine trial shows 94.1 percent efficacy
Results from the ongoing phase 3 clinical trial demonstrate efficacy in preventing symptomatic COVID-19 infections and severe illness. …
Read Full ArticleCommon diabetes drug may trigger rare complications for COVID-19 patients
Diabetes patients on glucose-lowering drugs may be at increased risk for diabetic ketoacidosis when they contract COVID-19. …
Read Full ArticleBreast cancer study uncovers how macrophages may contribute to a therapeutic weak spot
Immunosuppressive macrophages may exacerbate the breast cancer microenvironment, dampening the benefits of PARP inhibitor therapy. …
Read Full ArticleBlood test for alzheimer’s disease predicts future cognitive decline in healthy people
Levels of an N-terminal fragment of tau protein in blood predict future cognitive decline and Alzheimer’s disease. …
Read Full ArticleYoung people hospitalized with COVID-19 face substantial adverse outcomes
Researchers found 21 percent of young adults (aged 18-34) hospitalized with COVID-19 required intensive care, 10 percent required mechanical ventilation and 2.7 percent died. …
Read Full ArticleNo improvement in death rate for COVID-19 patients who received hydroxychloroquine
A large observational study finds hospitalized COVID-19 patients who received hydroxychloroquine or chloroquine had worse outcomes and heightened risk of ventricular arrhythmias. …
Read Full ArticleIrregular sleep may increase risk of cardiovascular events
Irregular sleep patterns could cause more than two-fold increase in cardiovascular risk. …
Read Full ArticleNew technique predicts which melanoma patients are at risk for metastatic recurrence
Primary melanoma patients with lower T-cell fraction are 2.5 times more likely to have cancer metastasize than patients with higher T-cell fraction. …
Read Full ArticleNanoparticle therapeutic restores tumor suppressor, sensitizes cancer cells to treatment
In preclinical experiments, investigators restored tumor suppressor p53 using synthetic mRNA nanoparticles, making cancer cells susceptible to available cancer drugs. …
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