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Posts by Brigham and Women's Hospital

Nanoparticle drug-delivery system developed to treat brain disorders

Brigham and Women's Hospital | 01-01-2021

Use of a nanoparticle drug-delivery system in mouse models results in unprecedented siRNA penetration across the blood-brain barrier. …

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Moderna COVID-19 vaccine trial shows 94.1 percent efficacy

Brigham and Women's Hospital | 12-30-2020

Results from the ongoing phase 3 clinical trial demonstrate efficacy in preventing symptomatic COVID-19 infections and severe illness. …

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Common diabetes drug may trigger rare complications for COVID-19 patients

Brigham and Women's Hospital | 12-24-2020

Diabetes patients on glucose-lowering drugs may be at increased risk for diabetic ketoacidosis when they contract COVID-19. …

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Breast cancer study uncovers how macrophages may contribute to a therapeutic weak spot

Brigham and Women's Hospital | 12-18-2020

Immunosuppressive macrophages may exacerbate the breast cancer microenvironment, dampening the benefits of PARP inhibitor therapy. …

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Blood test for alzheimer’s disease predicts future cognitive decline in healthy people

Brigham and Women's Hospital | 12-09-2020

Levels of an N-terminal fragment of tau protein in blood predict future cognitive decline and Alzheimer’s disease. …

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Young people hospitalized with COVID-19 face substantial adverse outcomes

Brigham and Women's Hospital | 10-08-2020

Researchers found 21 percent of young adults (aged 18-34) hospitalized with COVID-19 required intensive care, 10 percent required mechanical ventilation and 2.7 percent died. …

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No improvement in death rate for COVID-19 patients who received hydroxychloroquine

Brigham and Women's Hospital | 05-22-2020

A large observational study finds hospitalized COVID-19 patients who received hydroxychloroquine or chloroquine had worse outcomes and heightened risk of ventricular arrhythmias. …

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Irregular sleep may increase risk of cardiovascular events

Brigham and Women's Hospital | 03-02-2020

Irregular sleep patterns could cause more than two-fold increase in cardiovascular risk. …

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New technique predicts which melanoma patients are at risk for metastatic recurrence

Brigham and Women's Hospital | 01-20-2020

Primary melanoma patients with lower T-cell fraction are 2.5 times more likely to have cancer metastasize than patients with higher T-cell fraction. …

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Nanoparticle therapeutic restores tumor suppressor, sensitizes cancer cells to treatment

Brigham and Women's Hospital | 12-23-2019

In preclinical experiments, investigators restored tumor suppressor p53 using synthetic mRNA nanoparticles, making cancer cells susceptible to available cancer drugs. …

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