Posts by University of Pennsylvania School of Medicine
Blocking specific protein could provide new treatment for deadly form of prostate cancer
New findings show that blocking a protein kinase known as CDK7 sets off a chain reaction that results in the death of prostate cancer cells …
Read Full ArticleHelping skin cells differentiate could be key to treating common skin cancer
New study identifies epigenetic regulator that plays a key role in the growth of non-melanoma skin cancers. …
Read Full ArticleTaking out the protein garbage becomes more difficult as neurons age
Penn study finds that as cells age, their ability to remove damaged proteins and structures declines, which could be a risk factor for neurodegenerative brain diseases. …
Read Full ArticleCardiac genetic mutation may not always predict heart disease
Researchers find only 5 percent of patients with a mutation of the TTN gene have dilated cardiomyopathy, despite changes in heart function. …
Read Full ArticleNew immunotherapy – chemotherapy combination can shrink pancreatic tumors
A new combination of immunotherapy and chemotherapy for pancreatic cancer caused tumors to shrink in the majority of evaluable patients …
Read Full ArticleCervicovaginal microbiome linked to spontaneous premature birth
Seven types of bacteria and certain immune factors in a woman’s vagina and cervix may be responsible for increasing the risk of spontaneous preterm birth (sPTB) or protect against it, …
Read Full ArticleEnergizing the immune system to eat cancer
Immune cells called macrophages are supposed to serve and protect, but cancer has found ways to put them to sleep. …
Read Full ArticleInjection improves vision in a form of childhood blindness
A new treatment for patients with a form of congenital retinal blindness has shown success in improving vision, according to results published today in Nature Medicine …
Read Full ArticleGlobal trial shows CAR T-cell therapy can lead to durable remissions in non-Hodgkin’s lymphoma
In an update to a global clinical trial stretching from Philadelphia to four continents, the chimeric antigen receptor (CAR) T cell therapy Kymriah® …
Read Full ArticleBeing older helps skin heal with less scarring, and now researchers know why
A compound secreted in the bloodstream could be the key factor that causes wounds in older people to heal with less scarring than in younger people. The compound is called stromal cell-derived-factor-1 (SDF1), …
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