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Posts by University of Pennsylvania School of Medicine

Hormone drugs may disarm SARS-CoV-2 spike protein and stop COVID-19 progression

University of Pennsylvania School of Medicine | 03-22-2021

Hormone drugs that reduce androgen levels may help disarm the SARS-CoV-2 spike protein used to infect cells and stop the progression of severe COVID-19. …

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Off-the-shelf immune drug shows promise in aggressive multiple myeloma

University of Pennsylvania School of Medicine | 12-05-2020

Teclistamab injection found to be safe and elicit responses in 74 percent of patients with relapsed/refractory multiple myeloma. …

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Magnetic field and hydrogels could be used to grow new cartilage

University of Pennsylvania School of Medicine | 10-19-2020

New research shows that it’s possible to use a magnetic field and hydrogels to rebuild complex body tissues …

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Scientists engineer antimicrobial molecules from wasp venom

University of Pennsylvania School of Medicine | 10-12-2020

Scientists have engineered powerful new antimicrobial molecules from toxic proteins found in wasp venom. …

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Researchers uncover epigenetic drivers for Alzheimer’s disease

University of Pennsylvania School of Medicine | 09-28-2020

New findings suggest that late-onset Alzheimer’s disease is driven by epigenetic changes — how and when certain genes are turned on and off — in the brain. …

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Middle-aged individuals may be in a perpetual state of H3N2 influenza virus susceptibility

University of Pennsylvania School of Medicine | 09-11-2020

Middle-aged individuals born in the late 1960s and the 1970s may be in a perpetual state of H3N2 influenza virus susceptibility …

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Investigational drug stops toxic proteins in neurodegenerative diseases

University of Pennsylvania School of Medicine | 09-08-2020

A preclinical study finds that toxic proteins from the mutated C9orf72 gene stimulate TDP-43 clumping, a well-known hallmark of neurodegenerative diseases. …

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Activating an estrogen receptor can stop pancreatic cancer cells from growing

University of Pennsylvania School of Medicine | 05-04-2020

Activating the G protein-coupled estrogen receptor (GPER) stops pancreatic cancer from growing and also makes tumors more visible to the immune system …

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Blood test may help doctors catch pancreatic cancer early

University of Pennsylvania School of Medicine | 04-16-2020

Study shows liquid biopsy may be a viable option for both diagnosis and staging of pancreatic cancer. …

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PARP inhibitor drugs can be ‘tuned’ for better killing of tumor cells

University of Pennsylvania School of Medicine | 04-10-2020

Cancer-killing “PARP inhibitor” drug that has struggled to show effectiveness in clinical trials can be structurally modified to greatly increase its power to kill tumor cells. …

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