Posts by University of Pennsylvania School of Medicine
Common gene variants linked to sepsis and COVID-19 severity in African Americans
Two genetic risk variants that are carried by nearly 40 percent of African Americans may exacerbate the severity of both sepsis and COVID-19. …
Read Full ArticleRobust T-cell response to mRNA COVID-19 vaccines — a more durable source of protection
mRNA COVID-19 vaccines provoke a swift and strong T-cell response, potentially providing a durable source of protection. …
Read Full ArticleImmune-activating drug blocks multiple SARS-CoV-2 variants in mice
The drug diABZI — which activates the body’s innate immune response — was highly effective in preventing severe COVID-19 in mice infected with SARS-CoV-2. …
Read Full ArticleHormone drugs may disarm SARS-CoV-2 spike protein and stop COVID-19 progression
Hormone drugs that reduce androgen levels may help disarm the SARS-CoV-2 spike protein used to infect cells and stop the progression of severe COVID-19. …
Read Full ArticleOff-the-shelf immune drug shows promise in aggressive multiple myeloma
Teclistamab injection found to be safe and elicit responses in 74 percent of patients with relapsed/refractory multiple myeloma. …
Read Full ArticleMagnetic field and hydrogels could be used to grow new cartilage
New research shows that it’s possible to use a magnetic field and hydrogels to rebuild complex body tissues …
Read Full ArticleScientists engineer antimicrobial molecules from wasp venom
Scientists have engineered powerful new antimicrobial molecules from toxic proteins found in wasp venom. …
Read Full ArticleResearchers uncover epigenetic drivers for Alzheimer’s disease
New findings suggest that late-onset Alzheimer’s disease is driven by epigenetic changes — how and when certain genes are turned on and off — in the brain. …
Read Full ArticleMiddle-aged individuals may be in a perpetual state of H3N2 influenza virus susceptibility
Middle-aged individuals born in the late 1960s and the 1970s may be in a perpetual state of H3N2 influenza virus susceptibility …
Read Full ArticleInvestigational drug stops toxic proteins in neurodegenerative diseases
A preclinical study finds that toxic proteins from the mutated C9orf72 gene stimulate TDP-43 clumping, a well-known hallmark of neurodegenerative diseases. …
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