New research shows that blocking the protein responsible for lactic acid uptake in exhausted T cells revitalizes their energy and enhances tumor control in mouse cancer models. …
A study in mice found that immune-stimulating protein fragments, called guardian peptides, are produced by the brain and spinal cord to maintain the brain’s immune balance, allowing for healthy communication with the immune system. …
Researchers have discovered a mechanism that ovarian tumors use to weaken immune cells and hinder their attack by blocking the energy supply that T cells rely on. …
Study reveals new understanding of the eye’s natural defense against uveitis and inflammation. …
Findings from the international FORT-2 clinical trial indicate that a promising combination treatment that includes immunotherapy is safe and well-tolerated in patients with locally advanced or metastatic bladder cancer. …
A large clinical trial has shown that an immunotherapy drug may nearly double the time that high-risk, muscle-invasive bladder cancer patients remain cancer-free after bladder removal surgery. …
Scientists have developed an immunotherapy that protects neurons from immune cell attack at the site of traumatic spinal cord injury. …
A novel tool that tracks immune health over time has revealed how a pair of checkpoint inhibitor therapies work together to recruit new cancer-fighting T cells with each infusion. …
New study identifies a molecular mechanism underlying regulatory T cell dysfunction in multiple sclerosis and other autoimmune diseases. …
Researchers have shown in mice a new approach to fighting pancreatic cancer that utilizes a novel nanoparticle drug-delivery system to activate an immune pathway alongside tumor-targeting agents. …
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