Posts by University of California - San Diego
Protein that dampens immune response could form basis for new therapeutics
Treatment with a peptide that mimics a naturally occurring protein prevents immune overreaction in mouse models. …
Read Full ArticlePersonalized cancer therapy improves outcomes in advanced disease
Study finds patients receiving care for advanced cancer were more likely to survive or experience improved outcomes if they received personalized cancer therapy. …
Read Full ArticleStatins reduce COVID-19 severity, likely by removing cholesterol that virus uses to infect
Researchers discovered that cholesterol-lowering statins reduced the risk of severe COVID-19 infection and uncovered a cellular mechanism that helps explain why. …
Read Full ArticleSARS-CoV-2 entry into host cells requires heparan sulfate and ACE2
Researchers have discovered that SARS-CoV-2 entry into host cells requires both ACE2 and a carbohydrate called heparan sulfate. …
Read Full ArticleHow loss of single gene fuels deadly childhood brain cancer
Using stem cells, researchers describe how the inactivation of the SMARCB1 gene blocks developing neurons and promotes tumor development. …
Read Full ArticleCommon class of drugs linked to increased risk of Alzheimer’s disease
Anticholinergic medications are used for many conditions but might also accelerate cognitive decline, especially in older persons with biological or genetic risk factors. …
Read Full ArticleInflammatory bowel disease linked to an immune cell run amok
New findings may provide new therapeutic target and help explain why inflammatory bowel disease (IBD) and other autoimmune diseases are often chronic and life-long. …
Read Full ArticleExcessive fructose consumption may cause a leaky gut, leading to fatty liver disease
Mouse studies suggest that finding ways to prevent disruption of the intestinal barrier by high fructose corn syrup could avoid subsequent non-alcoholic fatty liver disease. …
Read Full ArticleFlipping a metabolic switch to slow tumor growth
The enzyme serine palmitoyl-transferase can be used as a metabolically responsive “switch” that decreases tumor growth …
Read Full ArticleImplanted neural stem cell grafts show functionality in spinal cord injuries
In mouse studies, specialized neural stem cell grafts integrated with host neural networks and behaved much like neurons in a healthy, undamaged spinal cord. …
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