Posts by University of California - San Diego
Human gut-in-a-dish model helps define ‘leaky gut,’ and outline a pathway to treatment
Researchers simulate leaky gut conditions for the first time, using 3D models of human intestines generated from patient cells. …
Read Full ArticleAssessing ‘stickiness’ of tumor cells could improve cancer prognosis
A team of researchers has created a device that measures how “sticky” cancer cells are, which could improve prognostic evaluation of patient tumors. …
Read Full ArticleOpioid dependence found to permanently change brains of rats
Study found that opioid dependence produced permanent changes in the neural network modulating pain transmission in rats. …
Read Full ArticleEating more produce will not cure, stop prostate cancer
Diets bolstered by more fruits and vegetables produced no extra protection from the increased micronutrients in early-stage prostate cancer patients. …
Read Full ArticleMeasuring mutations in sperm may reveal risk for autism in future children
Spontaneous mutations in paternal sperm are linked to autism spectrum disorder; researchers have developed a way to quantify those mutations and assess chances the mutations will cause disease. …
Read Full ArticleGenetic variation in individual brain cell types may predict disease risk
Major genetic risk allele for Alzheimer’s disease is linked to non-coding regions of the genome called enhancers that are selectively active in microglia, the major immune cell in the brain. …
Read Full ArticlePhage therapy shows promise for alcoholic liver disease
Gut bacteria toxin linked to worse clinical outcomes in patients with alcoholic liver disease; treatment with bacteriophages clears the bacteria and eliminates the disease in mice. …
Read Full ArticlePopular pain medication associated with greater risk of hypoglycemia
Tramadol, an opioid, is widely used to treat moderate or severe pain, but patients may be at risk of low blood sugar levels. …
Read Full ArticleAdding MS drug to targeted cancer therapy may improve glioblastoma outcomes
By reaching stem cells at the tumor’s root, multiple sclerosis drug teriflunomide, paired with targeted cancer therapy, markedly shrinks patient-derived glioblastomas grown in mice. …
Read Full ArticleResearchers map protein-gene interactions involved in Alzheimer’s disease
Researchers have identified changes in gene activity associated with Alzheimer’s disease. …
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