Posts by University of California - San Diego
Novel drug prevents amyloid plaques, a hallmark of Alzheimer’s disease
In animal models, the new compound modulated a key enzyme, reducing or eliminating production of problematic protein fragments associated with amyloid plaques. …
Read Full ArticleNew skin patch brings us closer to wearable, all-in-one health monitor
Engineers have developed a soft, stretchy skin patch that can be worn on the neck to continuously monitor cardiovascular signals and multiple biochemical levels …
Read Full ArticleTime-restricted feeding reduces breast cancer risk in obese mice
Time-restricted feeding improved metabolic health and reduced tumor growth in mice with obesity-driven postmenopausal breast cancer. …
Read Full ArticleDesigner DNA therapeutic treats multiple myeloma in mice
A new targeted approach to multiple myeloma treatment silences the IRF4 gene that allows myeloma stem cells and tumor cells to proliferate and survive. …
Read Full ArticleMetabolism may play role in recurrent major depression
Researchers find that metabolites — small molecules produced by cellular activities — appear to predict risk of recurring depression …
Read Full Articlee-cigarettes trigger gut barrier disruption and inflammation
Chemicals found in e-cigarettes disrupt the gut barrier and trigger inflammation, potentially leading to a variety of health concerns. …
Read Full ArticleBreaking bad: how shattered chromosomes make cancer cells drug-resistant
Researchers describe how a phenomenon known as “chromothripsis” breaks up chromosomes, which then reassemble in ways that ultimately promote cancer cell growth. …
Read Full ArticleResearchers discover clue to how to protect neurons and encourage their growth
By inhibiting a particular family of enzymes, it may be possible to develop new therapies for treating neurodegenerative diseases from glaucoma to Alzheimer’s. …
Read Full ArticleProtein that dampens immune response could form basis for new therapeutics
Treatment with a peptide that mimics a naturally occurring protein prevents immune overreaction in mouse models. …
Read Full ArticlePersonalized cancer therapy improves outcomes in advanced disease
Study finds patients receiving care for advanced cancer were more likely to survive or experience improved outcomes if they received personalized cancer therapy. …
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