Posts by University of California - San Diego
Opposite effect: Protein widely known to fight tumors also boosts cancer growth
Search for a description of “p53” and it becomes clear that this human protein is widely known for its cancer-fighting benefits, leading to its renown as “the guardian of the genome.” …
Read Full ArticleResearchers find a ‘druggable target’ for treating Alzheimer’s disease
The accumulation of amyloid beta (Aβ) plaques and tangles of a protein called tau in the brain are hallmarks of Alzheimer’s disease (AD). …
Read Full ArticleLow-sugar diet effective in boys with nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease in children and is associated with type 2 diabetes, end-stage liver disease, liver cancer and cardiovascular disease. …
Read Full ArticleAn errant editing enzyme promotes tumor suppressor loss and leukemia propagation
Researchers at University of California San Diego School of Medicine report that detection of “copy editing” by a stem cell enzyme called ADAR1, which is active in more than 20 tumor types, …
Read Full ArticleResearchers identify how skin ages, loses fat and immunity
Dermal fibroblasts are specialized cells deep in the skin that generate connective tissue and help the skin recover from injury. Some fibroblasts have the ability to convert into fat cells that reside under the dermis, …
Read Full ArticleResearchers develop sensors to detect and measure cancer’s ability to spread
The spread of invasive cancer cells from a tumor’s original site to distant parts of the body is known as metastasis. It is the leading cause of death in people with cancer. …
Read Full ArticleNew cancer immunotherapy approach turns immune cells into tiny anti-tumor drug factories
Cancer immunotherapy — efforts to better arm a patient’s own immune system to attack tumors — has shown great potential for treating some cancers. Yet …
Read Full ArticleImmunotherapy better than chemotherapy for subtype of head and neck cancer
A randomized clinical trial involving 97 medical centers in 20 countries, including Moores Cancer Center at UC San Diego Health, found that treating patients who have chemotherapy-resistant head and neck cancer …
Read Full ArticleInfectious prions detected in eyes of CJD patients
By the time symptoms of sporadic Creutzfeldt-Jakob disease (sCJD) are typically discovered, death is looming and inevitable. But, in a new study, researchers at University of California San Diego …
Read Full ArticleKawasaki disease: One inflammatory disease, multiple triggers
Researchers at the University of California San Diego School of Medicine, Scripps Institution of Oceanography, and international collaborators have evidence that Kawasaki Disease (KD) does not have a single cause. …
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