Posts by Institute of Cancer Research
New evolution-busting drug overcomes resistance in aggressive breast cancers
A new type of drug that blocks one of cancer’s key evolutionary escape routes from chemotherapy could be used to treat aggressive breast cancers, …
Read Full ArticleAI reveals new breast cancer types that respond differently to treatment
Scientists have used artificial intelligence to recognize patterns in breast cancer – and uncovered five new types of the disease each matched to different personalized treatments. …
Read Full ArticleNew treatment could become first targeted therapy designed for ‘untreatable’ childhood brain cancer
A new type of drug that targets a genetic weakness in an untreatable childhood brain cancer could become the first ever treatment designed to target the disease. …
Read Full ArticleCancers ‘change spots’ to avoid immunotherapy
Cancers can make themselves harder for new immunotherapies to see by ‘changing their spots’ – and switching off a key molecule on the cell surface. …
Read Full ArticlePrecision drugs could unmask cancers to immune system and boost effects of immunotherapy
Precision cancer drugs called PARP inhibitors have a previously unknown ability to boost immune responses, and could help many more patients benefit from immunotherapy, …
Read Full ArticleNew ‘Trojan horse’ cancer treatment shows early promise in multiple tumor types
A brand new type of cancer drug that acts as a ‘Trojan horse’ to get inside tumor cells has shown promise in patients with six different cancer types. …
Read Full ArticleImmunotherapy effective as first-line treatment for advanced head and neck cancer
Immunotherapy on its own is better than aggressive chemotherapy as a first-line treatment for advanced head and neck cancer, according to surprising new data from a major phase III clinical trial. …
Read Full ArticleProstate cancer DNA test identifies men with six-fold increased risk
A major new study of more than 140,000 men has identified 63 new genetic variations in the DNA code that increase the risk of prostate cancer. …
Read Full ArticleStunting cell ‘antennae’ could make cancer drugs work again
Scientists have uncovered a completely new way to make cancers sensitive to treatment – by targeting antenna-like structures on cells. Their study found that drug-resistant cancer cells have more and longer antennae …
Read Full ArticleScientists identify cause of resistance to breakthrough breast and ovarian cancer drug
Scientists have identified a mutation that gives cancer cells resistance to the breakthrough cancer treatment olaparib and other PARP inhibitors. …
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