A population-level retrospective cohort study found that common medications can trigger prescribing cascades in older adults, leading to additional drugs for side effects and increasing medication-related harm and healthcare costs. …
A multicenter randomized clinical trial found that high-frequency spinal cord stimulation significantly reduced pain and improved sensory function in people with treatment-resistant painful diabetic neuropathy. …
Two international clinical trials found that the investigational biologic therapy tozorakimab significantly reduced COPD flare-ups in patients receiving standard treatment. …
New findings show that inhibitory neurons form synapses with glioma cells, suppress tumor growth, and extend survival in mouse and patient-derived models. …
Scientists found that bacteria in the urinary tract can convert the steroid precursor DHEA into testosterone, potentially influencing hormone-driven prostate cancer. …
Researchers found that the T cells driving neurodegeneration in Alzheimer’s disease and related disorders originate in lymph nodes outside the brain. …
Cancer cells evade T cell attacks by removing reactive oxygen species from the tumor environment that are needed for immune signaling, making this process a promising immunotherapy target. …
Researchers have created a detailed single-cell map of childhood Crohn’s disease before and after treatment which suggests anti-TNF therapy might push the pediatric cell ecosystem towards more resistant disease. …
Study finds starting statin therapy soon after a type 2 diabetes diagnosis is associated with a lower risk of dementia. …
A phase 2 clinical trial found that an investigational anti-IL-6 antibody sustainably reduced inflammation biomarkers for six months in patients with chronic kidney disease and elevated cardiovascular risk. …
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