Tirzepatide, a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes and obesity, can reduce the risk of heart attacks and hospitalizations due to infections by about one-third compared to conventional diabetes treatments. …
Scientists have shown that abnormal tau proteins, altered by enzymatic changes, infiltrate mitochondria in neurons, disrupting energy production and triggering a harmful cycle linked to Alzheimer’s and other neurodegenerative diseases. …
Phase 1 trial reports positive results for a brain-protective immunotherapy in early Alzheimer’s disease. …
A comprehensive study analyzing over 1.1 million lung tissue-resident immune cells reveals insights into how their dysfunction may contribute to lung inflammation and autoimmune diseases like lupus, rheumatoid arthritis, and scleroderma. …
New research has identified a strategy to make antibody-drug conjugates more effective against metastatic castration-resistant prostate cancer, potentially overcoming treatment resistance. …
Researchers have found that polyethylene microplastics may contribute to fatty liver disease and exacerbate its effects when combined with an unhealthy diet. …
A phase 3 clinical trial found that the cell therapy deramiocel may slow muscle weakening and heart damage in boys and young men with advanced Duchenne muscular dystrophy. …
Blocking autophagy, the cell’s recycling process, in specialized blood vessels reduces psoriasis inflammation without weakening the immune system, suggesting a new treatment for chronic inflammatory diseases. …
A new multi-center clinical study is shedding light on a potential approach for patients with advanced kidney cancer, providing measurable clinical responses and enhancing understanding of the underlying disease mechanisms. …
Off-the-shelf, mass-producible immune cells that fight solid human tumors engrafted into mice represent a significant advancement toward faster and more affordable cancer immunotherapy. …
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