Preclinical data shows combination immunotherapy could stop liver cancer growth
Even as overall cancer incidence and mortality decrease in the United States, the number of people diagnosed with liver cancer is on the rise. …
Breast cancer cells rely on pyruvate to spread to new tissues
Most patients who die of breast cancer die of metastasis, the process by which cancer cells spread to other organs of the body. Cancer cells alter their metabolism to grow …
Scientists discover potential way to treat and prevent neuroblastoma
The MYCN oncogene has long been known to be a key cause of a number of deadly solid tumor cancers, including neuroblastoma, which claims more lives of children …
Researchers identify immune cells responsible for inflammatory bowel disease flare-ups
More than 4000,000 people in Germany are affected by the chronic inflammatory bowel diseases, Crohn’s disease or ulcerative colitis. Patients often suffer from flare-ups, …
Virus-based therapy targets a pediatric eye cancer
A cancer-killing, virus-based therapy showed promising effects against retinoblastoma – a tumor of the retina that affects mainly children – in mouse models and a pilot clinical trial. …
Anti-inflammatory compound protects against ovarian cancer growth and recurrence in mice
A new anti-inflammatory compound developed at the University of California, Davis, acts as a “surge protector” to suppress inflammation and reduce cancer growth, at least in mouse models of cancer. …
Unconventional immune cells trigger disturbed cytokine production in human spondyloarthritis
Spondyloarthritis is one of the most common types of chronic joint inflammation affecting nearly 1-2% of the Western population. Cytokine blockade of Tumor necrosis factor (TNF) …
Tumors backfire on chemotherapy
Some patients with breast cancer receive chemotherapy before the tumor is removed with surgery. This approach, called ‘neoadjuvant’ therapy, helps to reduce the size of the tumor to facilitate breast-conserving surgery, …
Researchers identify how skin ages, loses fat and immunity
Dermal fibroblasts are specialized cells deep in the skin that generate connective tissue and help the skin recover from injury. Some fibroblasts have the ability to convert into fat cells that reside under the dermis, …
Tau protein suppresses neural activity in mouse models of Alzheimer’s disease
A study from Massachusetts General Hospital (MGH) investigators sheds new light on how the hallmarks of Alzheimer’s disease – amyloid-beta (A-beta) plaques and neurofibrillary tangles …
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