Researchers ready B cells for novel cell therapy
Scientists are paving the way to use gene-edited B cells — a type of white blood cell in the immune system — to treat a wide range of potential diseases that affect children, …
The unanticipated early origins of childhood brain cancer
Researchers have recently identified the cells that are thought to give rise to certain brain tumors in children and discovered that these cells first appear in the embryonic stage of a mammal’s development. …
Triple-negative breast cancers can adopt reversible state that is resistant to chemotherapy
Study finds triple-negative breast cancer (TNBC) cells can develop resistance to frontline, or neoadjuvant, chemotherapy not by acquiring permanent adaptations, …
Boosting muscle stem cells to treat muscular dystrophy and aging muscles
Lying within our muscles are stem cells, invisible engines that drive the tissue’s growth and repair. Understanding the signal(s) that direct muscle stem cells to spring into action …
Cancer-killing combination therapies unveiled with new drug-screening tool
Scientists have designed a large-scale screen that efficiently identifies drugs that are potent cancer-killers when combined, …
Vitamin B12 is identified as the inhibitor of a key enzyme in hereditary Parkinson’s disease
Parkinson’s is the most common, chronic neurodegenerative movement disorder affecting 1% of the global population over seventy years of age. …
New medication gives mice bigger muscles
Researchers have studied a new group of medications which could prove beneficial for the elderly and the chronically ill who suffer a loss of bone and muscle mass. …
Tumor-associated immune cells hinder frontline chemotherapy drug in pancreatic cancer
A frontline chemotherapy drug given to patients with pancreatic cancer is made less effective because similar compounds released by tumor-associated …
Researchers identify potential new therapy for liver diseases
Drug therapy may effectively treat a potentially life-threatening condition associated with cirrhosis and other chronic liver diseases, according to a new study by Mayo Clinic researchers. …
New drug combination shows promise for common pediatric brain tumor
A new combination treatment aimed at resistant and recurrent low-grade gliomas slowed tumor growth and killed tumor cells in laboratory and mouse models. …
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