Posts Tagged ‘gene expression’
Genetic variation in individual brain cell types may predict disease risk
Major genetic risk allele for Alzheimer’s disease is linked to non-coding regions of the genome called enhancers that are selectively active in microglia, the major immune cell in the brain. …
Read Full ArticleLeukemia cells can transform into non-cancerous cells through epigenetic changes
New report describes how a leukemia type B cell can transform into a different cell, a macrophage, …
Read Full ArticleGlutamine-blocking drug slows tumor growth and strengthens anti-tumor response
A compound that blocks glutamine metabolism can slow tumor growth, alter the tumor microenvironment and promote the production of durable and highly active anti-tumor T cells. …
Read Full ArticleOxygen-starved tumor cells have survival advantage that promotes cancer spread
Researchers say they have significant new evidence that tumor cells exposed to low-oxygen conditions have an advantage when it comes to invading and surviving in the bloodstream. …
Read Full ArticleGut instincts: Researchers discover first clues on how gut health influences brain health
Scientists have described for the first time new cellular and molecular processes underlying communication between gut microbes and brain cells. …
Read Full ArticleHealth in old age is a lifelong affair
Scientists have shown in mice that calorie restriction must be established earlier in life in order to improve health in old age and extend lifespan. …
Read Full ArticleMeningioma molecular profile reliably predicts tumor recurrence
Although typically benign, about one-fifth of meningiomas, the most common primary brain tumors, recur despite complete surgical removal. …
Read Full ArticleStudy explores blood-brain barrier leakage in CNS infections
A new study shines light on the breakdown of the blood-brain barrier (BBB) that occurs during many infections of the central nervous system. …
Read Full Articlep53 mutations in 10,000 cancer patients shed new light on gene’s function
Researchers have conducted the most comprehensive study of TP53 mutations to better understand the processes leading to the inactivation of this important gene in cancer. …
Read Full ArticleNew gene found for a deadly childhood cancer offers possibility of targeted drug therapy
Australian researchers have discovered that a gene called JMJD6 plays an important role in the most aggressive form of neuroblastoma. …
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