Plant flavonoid can significantly reduce blood pressure

Plant flavonoid can significantly reduce blood pressure. Credit: © Melpomene - Depositphotos

A new paper in Nutrition Reviews finds that intake of the flavonoid quercetin can greatly reduce high blood pressure in patients suffering from cardiovascular disease.

Researchers carried out a systematic review and meta-analysis of randomized controlled trials that assessed the impact of quercetin on blood pressure and glucose levels. Quercetin is a plant pigment commonly found in many plants and foods, such as onions, teas, apples, and red wine. Seventeen studies (886 participants) included in the analysis assessed blood glucose, total cholesterol, and/or insulin.

The pooled result from 13 treatment arms throughout the studies showed that quercetin administration markedly reduced systolic blood pressure. Participants who consumed quercetin for eight weeks or more showed significantly changed levels of high-density lipoprotein cholesterol. Quercetin did not markedly influence total cholesterol, or significantly alter fasting blood glucose concentrations. Quercetin was not found to cause serious adverse events in any of the included studies.

The review concluded that a reduction in blood pressure of more than 10 mmHg lowers cardiovascular risk by 50% for heart failure, 35% – 40% for stroke, and approximately 20% to 25% for myocardial infarction. Researchers found that the favorable effects of quercetin on blood pressure support the use of quercetin for patients with hypertension.


Materials provided by the Oxford University Press USA. Content may be edited for clarity, style, and length.


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