One in five “healthy” adults may carry disease-related genetic mutations

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DNA helix Credit: CC0 Creative Commons

Some doctors dream of diagnosing diseases—or at least predicting disease risk—with a simple DNA scan. But others have said the practice, which could soon be the foundation of preventative medicine, isn’t worth the economic or emotional cost. Now, a new pair of studies puts numbers to the debate, and one is the first ever randomized clinical trial evaluating whole genome sequencing in healthy people. Together, they suggest that sequencing the genomes of otherwise healthy adults can for about one in five people turn up risk markers for rare diseases or genetic mutations associated with cancers. …

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