CRISPR causes many unwanted mutations, small study suggests

Image: Thomas Splettstoesser (www.scistyle.com) - Own work, CC BY-SA 4.0

Does the CRISPR gene-editing method cause hundreds of extra, unwanted mutations? That’s the question raised by a small study in mice.

The idea of gene editing is to alter a single DNA sequence in the genome of cells while leaving the rest untouched. However, in practice, every gene-editing method sometimes results in unwanted changes. …

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