Posts by Cincinnati Children's Hospital Medical Center
Early clinical trial data show gene therapy reversing sickle cell anemia
After over a decade of preclinical research and development, a new gene therapy treatment for Sickle Cell Anemia (SCA) is reversing disease symptoms in two adults and showing early potential …
Read Full ArticleSickle cell anemia treatment safely lowers disease burden in African children
A daily hydroxyurea pill may finally bring some relief for young children living with the painful and deadly blood disease sickle cell anemia (SCA) in resource-challenged sub-Saharan Africa …
Read Full ArticleDetecting epigenetic signature may help people stay ahead of IBD
With an estimated 1.6 million people in the U.S. dealing with inflammatory bowel disease (IBD), physicians can have a hard time telling which newly diagnosed patients have a high risk of severe inflammation or what therapies …
Read Full ArticleOverall well-being of a population associated with less per capita healthcare spending
A new study in JAMA Network Open finds that the overall well-being of a population on a county level is associated with lower healthcare spending for each Medicare fee-for-service beneficiary. …
Read Full ArticleScientists block RNA silencing protein in liver to prevent obesity and diabetes in mice
Obesity and its related ailments like type 2 diabetes and fatty liver disease pose a major global health burden, but researchers report in Nature Communications that blocking an RNA-silencing protein …
Read Full ArticleStatin therapy effectively treats brutal lung disease
Researchers report in Nature Communications they figured out why air sacs in the lungs clog up with a thick substance called surfactant in a brutal disease called Pulmonary Alveolar Proteinosis (PAP), and they show taking cholesterol-busting pills called statins can effectively treat the disease. …
Read Full ArticleStudy reports possible novel method for stopping untreatable pediatric brain cancers
Researchers used an experimental molecular therapy in preclinical laboratory tests to effectively treat several types of deadly pediatric brain cancer and now propose advancing the treatment to clinical testing in children. …
Read Full ArticleBlocking matrix-forming protein might prevent heart failure
Scientists used an experimental targeted molecular therapy to block a matrix-forming protein in heart cells damaged by heart attack, reducing levels of scarred muscle tissue and saving mouse models from heart failure. ,,,
Read Full ArticleExperimental therapy restores nerve insulation damaged by disease
When the body attacks its own healthy tissues in an autoimmune disease, peripheral nerve damage handicaps people and causes persistent neuropathic pain when insulation on healing nerves doesn’t fully regenerate. …
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